LSMO-01 - Novel antimicrobials in the pipeline and the use of computational medicinal chemistry in finding new antimicrobial agents

Tracks
Room A1
Monday, September 1, 2025
13:00 - 14:00
Room A1

Details

Chair(s) MSc.Pharm Peter Thøgersen, Pharmadanmark, Denmark & Prof. Giovanni Pauletti, FIP Board of Pharmaceutical Sciences, USA Introduction: As antimicrobial resistance continues to challenge the effectiveness of existing treatments, the search for novel antimicrobial agents is gaining momentum. Advances in areas such as gene editing and computational medicinal chemistry are supporting innovative approaches to drug discovery. This session will explore the potential of CRISPR technology in targeting infectious diseases and examine scientific and practical considerations in developing the next generation of antibiotics. Through examples from research and industry, the session will consider how these tools are being applied to expand the antimicrobial pipeline. Programme:
13:00 – 13:05 Introduction by the chairs
13:05 – 13:30 The use of clustered regularly interspaced short palindromic repeats (CRISPR) technology in developing novel treatments against infection diseases
Dr Christian Grøndahl, SNIPR Biome, Denmark
13:30 – 13:55 Developing the next generation antibiotics – challenges and opportunities
Prof. Anders Karlén, Uppsala University, Sweden
13:55 – 14:00 Closing by the chairs
Learning objectives 1. Explore scientific approaches to antimicrobial drug discovery, including gene editing technologies and computational tools. 2. Understand key challenges and opportunities in developing next-generation antibiotics. 3. Consider how research and industry are contributing to the expansion of the antimicrobial pipeline through innovative methods. Take home messages Advancing the development of novel antimicrobial agents requires a combination of innovative scientific approaches, cross-sector collaboration, and sustained investment to address the growing threat of antimicrobial resistance. FIP Development Goals FIP DG 17 FIP DG 18 FIP DG 19 To learn more about these FIP Development Goals, click on the links below. FIP Development Goal 17: Antimicrobial Stewardship FIP Development Goal 18: Access to Medicines, Devices & Services FIP Development Goal 19: Patient Safety


Speakers

Agenda Item Image
Dr Christian Grøndahl
SNIPR Biome

SNIPR BIOME: CRISPR-based microbial gene therapies to address antimicrobial resistance, metabolic disorders, and immune conditions

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